Discover 25 of the most innovative biotech startups in Massachusetts that are hiring now in 2025. Explore careers in life sciences, biotech R&D & more.
🚀 25 Cutting-Edge Biotech Startups in Massachusetts That Are Hiring in 2025
Massachusetts has long been a powerhouse for biotechnology and life sciences innovation. As of 2025, the state continues to thrive with a new wave of biotech startups transforming healthcare, therapeutics, and diagnostics. Whether you’re a scientist, engineer, data analyst, or business development professional, there’s a role for you in this vibrant ecosystem.
Here are 25 of the most exciting biotech startups in Massachusetts currently hiring in 2025 — each on a mission to change the future of human health.
🌟 1. ODDITY LABS (formerly Revela)
Category: Beauty & Wellness Biotech
What They Do: A scientific engine in the beauty and wellness space, ODDITY LABS merges cutting-edge biotech with cosmetic innovation.
Why Join: Work at the intersection of synthetic biology and consumer beauty in a startup redefining the industry.
🔬 2. Stellaromics Inc.
Category: Genomics & Spatial Biology
What They Do: Building 3D transcriptional maps of native biological tissue to revolutionize how we view gene expression.
Why Join: Be part of groundbreaking spatial biology R&D with implications across oncology and neuroscience.
🧠 3. Seaport Therapeutics
Category: Neuropsychiatry
What They Do: Clinical-stage biotech developing next-gen treatments for mental health disorders with unmet needs.
Why Join: Shape the future of psychiatric medicine with novel small molecule and neuroactive drug development.
💊 4. Pledge Therapeutics
Category: Early Drug Discovery
What They Do: Translates clinical insights into drug targets and preclinical candidates using an integrated discovery platform.
Why Join: Be on the frontlines of precision medicine and translational drug research.
👩🔬 5. Scismic
Category: HR Tech for Biotech
What They Do: Tech platform helping biotechs build qualified, diverse, and NIH-compliant teams using algorithmic bias reduction.
Why Join: If you’re passionate about diversity, inclusion, and biotech hiring innovation, this is your place.
🧪 6. Compass Therapeutics Inc.
Category: Immuno-Oncology
What They Do: Develops antibody-based therapies to regulate angiogenesis and immune cell behavior in tumors.
Why Join: Contribute to first-in-class cancer immunotherapies entering clinical trials.
🔍 7. Nona Biosciences
Category: Antibody Discovery Services
What They Do: Offers complete antibody discovery pipelines from antigen prep to final optimization.
Why Join: Work with a global biotech with massive influence in immunotherapeutic innovation.
🧫 8. RoslinCT
Category: Advanced Cell & Gene Therapy CDMO
What They Do: Provides world-class cell and gene therapy manufacturing, leveraging the legacy of Dolly the Sheep.
Why Join: Join pioneers in regenerative medicine and advanced therapy production.
🛡️ 9. Marengo Therapeutics
Category: Immunotherapy
What They Do: Develops therapies that selectively boost T cells to fight cancer.
Why Join: A promising clinical-stage company unlocking new immune checkpoints.
🧬 10. Manifold Bio
Category: Protein Barcoding for Drug Design
What They Do: World’s first high-throughput in vivo drug design using protein barcoding.
Why Join: Be part of the team rewriting how protein-based drugs are created and tested.
🦠 11. Aviceda Therapeutics
Category: Glyco-Immunology
What They Do: Clinical-stage biotech focused on developing glycan-targeted therapies for immune modulation.
Why Join: Tackle inflammation and autoimmunity with novel glyco-therapeutics.
🔬 12. Merida Biosciences
Category: Autoimmune Therapeutics
What They Do: Precision medicine approach to eliminate pathogenic antibodies at the root of immune diseases.
Why Join: Perfect for immunology researchers and bioengineers.
🔥 13. Incendia Therapeutics
Category: Oncology
What They Do: Targeting the tumor microenvironment using innovative monoclonal antibodies.
Why Join: Work in a science-driven, fast-paced oncology biotech disrupting conventional treatment approaches.
💻 14. 1910 Genetics
Category: AI-Driven Drug Discovery
What They Do: Combines AI with lab automation to design drugs for both small and large molecules.
Why Join: Help merge computational biology with hands-on discovery.
🧫 15. QLD Biotherapeutics Inc.
Category: Cell & Gene Therapy
What They Do: R&D focused on developing next-gen gene therapies using proprietary delivery platforms.
Why Join: Early-stage startup with rapid growth potential and deep tech roots.
⚡ 16. Kytopen
Category: Genetic Engineering
What They Do: Delivers fast and scalable intracellular delivery of genetic material using non-viral methods.
Why Join: Support cutting-edge genetic editing for cancer and rare disease research.
🎯 17. Spear Bio
Category: Protein Detection Tech
What They Do: Developing the proprietary SPEAR platform for ultra-sensitive biomarker detection.
Why Join: Be part of a diagnostics revolution using dual authentication detection.
🦾 18. Vivtex
Category: GI Drug Delivery
What They Do: Robotics meets pharmacology in this startup’s GI-ORIS™ system for gut drug delivery analysis.
Why Join: Cutting-edge work with organoid modeling and robotic systems.
🚪 19. Portal
Category: Cell Engineering Platform
What They Do: Provides tech enabling next-gen cell engineering for R&D and clinical use.
Why Join: Empower research with intuitive, scalable platforms for biotech labs.
🔬 20. Cugene Inc.
Category: Immuno-Oncology
What They Do: Develops drugs targeting highly specific immune pathways for cancer and autoimmune diseases.
Why Join: Perfect for those who want to focus on precision immunology therapies.
🧠 Why Biotech Careers in Massachusetts Are Thriving in 2025
Massachusetts is home to Cambridge’s Kendall Square, often called “the most innovative square mile on the planet.” This area—and the broader Greater Boston region—is packed with venture-backed biotech startups, world-class academic centers like Harvard, MIT, and Broad Institute, and seasoned industry leaders.
Key trends in 2025:
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Increased VC funding and biotech IPOs
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Focus on AI in drug discovery
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Growth in precision and regenerative medicine
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A strong talent demand for R&D scientists, engineers, and data experts
💼 How to Get Hired by These Biotech Startups
If you’re actively job hunting in the biotech space:
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Tailor your resume to highlight specific skills (e.g., CRISPR, flow cytometry, protein purification)
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Follow each company on LinkedIn
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Sign up for alerts on biotech job boards (like BioSpace, Scismic, and MassBio Careers)
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Consider referral routes by connecting with current employees or joining local biotech networking groups
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Whether you’re a recent graduate, Ph.D., or a seasoned scientist, the biotech boom in Massachusetts offers a diverse array of high-impact roles across early discovery, clinical development, data science, and manufacturing. These 25 biotech startups are not only changing the face of medicine but also actively hiring in 2025.’
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